HIV-1 Drug Resistance Genotyping Kit Available only for CDC-supported pepfar genotyping laboratories
The CDC HIV-1 Pan Group-M Drug Resistance Genotyping Assay is now available as the ATCC® HIV-1 Drug Resistance Genotyping Kit* for surveillance of HIV-1 drug resistance in CDC-supported PEPFAR Genotyping Laboratories. This collaboration serves to bring investigators the trusted expertise of the CDC, supported by the excellence and quality of ATCC materials and reagents.
The HIV-1 Drug Resistance Genotyping Kit is intended for use in detecting HIV genomic mutations that confer resistance to specific types of antiretroviral (ARV) drugs, as an aid in monitoring HIV-1 drug resistance development and transmission. It can be used to:
- Detect multiple HIV-1 subtypes and circulating recombinant forms (CRFs) viral resistance in plasma (EDTA collected), Dried Blood Spots (DBS), or Dried Plasma Spots (DPS) with a viral load equal to or greater than 1000 copies/mL
- Genotype a specific region of HIV-1 RNA that includes the protease gene and the 5’ portion of the reverse transcriptase (RT) gene
Genotyping provides investigators with a genetic map to aid in monitoring the development and transmission of drug resistance mutations among an ARV-treated population or an ARV-treatment-naïve population recently diagnosed with HIV-infection.
*The ATCC HIV-1 Drug Resistance Genotyping Kit is not intended to be used as a screening test for HIV or as a diagnostic assay to confirm the presence of HIV infection.
Two modules are provided for genotyping, allowing for both detection & sequence analyses:
- Module 1: RT-PCR & Nested PCR (ATCC® GK-0098™)
- Module 2: Cycle Sequencing (ATCC® GK-0200™)
Orders are processed first as sales quotations, which should be requested by email.
The pepfar global initiative
Laboratories in countries partnered with PEPFAR support the U.S. Government initiative to help save the lives of those suffering from HIV/AIDS around the globe.
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