Recombinant Adeno-associated virus 2 (ATCC® VR-1616)

Classification: Parvoviridae, Dependovirus, Adeno-associated virus-2  /  Product Format: frozen

Permits and Restrictions

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Classification Parvoviridae, Dependovirus, Adeno-associated virus-2
Agent Recombinant Adeno-associated virus 2
Strain Recombinant Adeno-associated Virus 2 Reference Standard Stock (rAAV2 RSS)
Biosafety Level 2
Product Format frozen
Storage Conditions -70°C or colder
Comments For additional information on handling the Recombinant Adeno-associated Virus 2 Reference Standard Stock, view the AAVRSWG Handling Guide located on the ATCC website at www.atcc.org.
Growth Conditions
Temperature: 37°C
Name of Depositor Adeno-associated Virus Reference Standard Working Group (AAVRSWG)
References

Moullier P, Snyder, RO. International efforts for recombinant adeno-associated viral vector reference standards. Mol. Ther. 16:1185-1188, 2008.

Potter M, et al. Manufacture and stability study of the recombinant adeno-associated virus serotype 2 vector reference standard. BioProcessing Journal 7:8-14, 2008.

Burger C. et al. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Molecular Therapy : 10(2):302-17, 2004 PubMed: 15294177

Flotte TR, e al. Utility of a recombinant adeno-associated viral vector reference standard. BioProcessing J. 1: 75, 2002.

Chadeuf G, et al. Efficient recombinant adeno-associated virus production by a stable rep-cap HeLa cell line correlates with adenovirus-induced amplification of the integrated rep-cap genome. J. Gene Med. 2(4):260-268, 2000. PubMed: 10953917.

Grimm D, et al. Novel tools for production and purification of recombinant adeno-associated virus vectors. Human Gene Therapy 9: 2745-2760, 1998.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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