Murine hepatitis virus (ATCC® VR-246)

Classification: Nidovirales, Coronaviridae, Coronavirus,Group 2  /  Product Format: frozen

Classification Nidovirales, Coronaviridae, Coronavirus,Group 2
Agent Murine hepatitis virus
Strain Original (Friend)
Common Name Murine hepatitis virus
Applications
Stored material should by passed 1-2 times before being used for large-scale experiments.
Biosafety Level 2
Isolation
Isolated in hybrid (C58 X Bagg albino) mice inoculated with line I leukemia from C58 mice (MacDowell)
Product Format frozen
Storage Conditions -70°C or colder
Comments
Adult Swiss mice show signs of the disease but usually recover. Stored material should by passed 1-2 times before being used for large-scale experiments.
Effect on Host
Yes, in vivo effects: Death, liver necrosis
Death, liver necrosis.
Recommended Host
8 to 10 gram mouse, i.p. inoculation

Recommended Host:  M (8-10 gm, i.p.).

Host Range: sM (PR 1).

Host Range: sM (PR 1).

suckling mouse
Growth Conditions
Incubation: 3-5 days
Effect on Host
Yes, in vivo effects: Death, liver necrosis
Death, liver necrosis.
Name of Depositor C Friend
Special Collection ATCC
Source
Isolated in hybrid (C58 X Bagg albino) mice inoculated with line I leukemia from C58 mice (MacDowell)
References

Friend C, Braunsteiner H. Viral hepatitis associated with transplantable mouse leukemia. I. Acute hepatic manifestations following treatment with urethane or methylformamide. J. Exp. Med. 100: 665-674, 1954. PubMed: 13211922