Assay Development

Assays that provide robust and reliable data are critical for all areas of biological research, particularly with regard to microbial identification, drug and vaccine development, and patient care. Developing an assay that demonstrates sensitivity, specificity, and reproducibility relies on authenticated and validated standards and cell models.

ATCC is committed to providing scientists with innovative solutions that support every stage of the assay development and validation process. Here, we provide educational content to guide researchers in the selection of standards and cell models needed for evaluating inclusivity and exclusivity, the limit of detection, drift, and run-to-run variability.

Featured Content

3 Things to Know about Molecular-based Assays

Find guidance on selecting the controls needed to support assay validation and the evaluation of analytical performance.

Effective Tools for High-throughput Screening

A discussion on the use of Corning Epic Technology and the ATCC EGFR Genetic Alteration Panel for screening ligands or biologics that target or affect EGFR receptor biology.

Advancing Standards for Clinical Diagnostics

Learn more about the need for standards in clinical laboratory testing and how ATCC supports this need with authenticated biological and molecular reference materials.

Improved In Vitro Model of Angiogenesis

A discussion on the use of a novel high-throughput model for evaluating angiogenesis in cancer, cardiovascular disease, wound healing, and other pathologies.

Development and Use of Microbiome Standards

A study demonstrating the use of whole cell– and genomic DNA–based microbiome reference materials in method optimization and data interpretation.

Want to Standardize your Microbiome Research?

A discussion on the need for standardization in microbiome research and how ATCC has addressed this by combining the power of physical standards with state-of-the-art bioinformatics.

Quantitative Controls for Evaluating Sensitivity

Explore how the use of quantitative external DNA controls provides an effective approach for the development and evaluation of novel molecular-based mycoplasma detection assays.

Quantitative Synthetic Dengue Virus RNA

A proof-of-concept study demonstrating how synthetic molecular standards can be used to develop a standard curve for quantifying viral RNA extracted from representative Dengue serotypes.

Empower Your Molecular-based Assays

Learn more about the use of authenticated and quantitative nucleic acids in developing assays for oncology molecular diagnostics, infectious disease research, and quality control testing.