Induced Pluripotent Stem Cell Repository for Human Tissue and Disease Models

6/15/2011 — 6/18/2011

Presented at the ISSCR meeting

Abstract: Induced pluripotent stem cells (iPSCs) have the potential to transform biomedical research and drug discovery. However, several hurdles exist for the free dissemination of these research materials, so the cells are difficult to obtain from other laboratories. Therefore, rates of sharing for iPSCs are not what they could be. ATCC is working to create a repository of iPSC materials to enable wider and faster access to iPSCs to support the research community. By professionally managing the roadblocks to reagent distribution as a biorepository, ATCC accelerates research advances by facilitating the sharing and distribution of iPSC. The organization also is establishing a mechanism to protect the commercial interests of stakeholders while still enabling commercial use of these materials. The organization strives to make it easy to contribute cells, as well as easy to access these materials. It has instituted standard processes and quality control procedures for iPSCs, which will improve consistency and reliability when used in research. In addition, the use of materials transfer agreements help define commercial use to avoid potential disputes. ATCC has recently licensed the rights to use technology from the laboratory of Prof. Shinya Yamanaka (Kyoto University) for reprogramming genes to create iPSCs, and is pursuing the rights to distribute cells created by other methods.