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Application of hTERT-immortalized Primary Cells in Toxicological Assays

Application of hTERT-immortalized Primary Cells in Toxicological Assays

Developing cell-based assays can be problematic; the cells must be physiologically relevant for the assay to be predictive, yet sufficiently abundant to be included in the assay without introducing interexperimental variability. hTERT-immortalized primary cells address both issues. hTERT-immortalized primary cells exhibit the growth characteristics of continuous cell lines while providing the physiological attributes of primary cells. In this presentation, ATCC experts will discuss the characteristics of hTERT-immortalized primary cells derived from the kidney, skin, airway, and vasculature and will describe the versatility of these cells in toxicological assays.