ATCC - Leading the Fight Against "Superbugs"

Carbapenem-Resistant Strains

The carbapenems are a class of β-lactam antibiotics commonly used as a last resort treatment against drug-resistant infections. In recent decades, there have been growing concerns regarding the emergence of carbapenem-resistance among bacteria, particularly among species within the Enterobacteriaceae family.

To support the research against these superbugs, ATCC has acquired a number of carbapenem-resistant Enterobacteriaceae (CRE) strains from various clinical sources. Each strain was confirmed to carry either the blaKPC or blaNDM gene, conferring resistance to carbapenem antibiotics. Moreover, a number of these strains exhibit multidrug-resistance to as many as 36 representative antibiotics, making them ideal tools for the development, verification, and evaluation of:

  • Rapid detection methods
  • Innovative therapeutic techniques
  • Novel antibiotics
  • Updated sterility protocols

Here, we provide a list of recognized carbapenemases and their known bacterial carriers.  Please use the links below to view a complete listing of available CRE strains from ATCC. For more information on multidrug-resistance, please visit our Multidrug-Resistant Reference Strains page.


Carbapenemase Ambler Class Known Bacterial Carriers
GES A K. pneumoniae, E. coli, P. aeruginosa
IMI A E. cloacae
KPC A K. pneumoniae, E. coli, Enterobacter spp.
NMC A E. cloacae
SME A S. marcescens
GIM B E. cloacae
IMP B P. aeruginosa, S. marcescens, B. fragilis, A. baumannii
NDM B E. coli, K. pneumoniae, E. cloacae
SIM B P. aeruginosa, A. baumannii
SPM B P. aeruginosa
VIM B P. aeruginosa
OXA D K. pneumoniae, E. coliAcinetobacter spp., P. aeruginosa, Providencia rettgeri