Skin cancer

Melanomas are derived from cells that secrete melanin, a pigment that, paradoxically, protects the body from ultra-violet light-induced DNA damage. By contrast, non-melanoma skin cancers such as basal cell carcinoma and squamous cell carcinoma arise from keratinocytes, the cells that provide the functional epidermal barrier. ATCC has a variety of dermal cell types applicable to cancer research applications.

Skin Cancer Panels

ATCC has developed two melanoma cancer cell panels with varying degrees of genetic complexity, representing both primary and metastatic tumors. To investigate genetic abnormalities in the context of your gene of interest and other tissues, ATCC has panels of cell lines organized by genetic alteration.

Melanoma Cell Panels

Genetic Alteration Panels

Primary and hTERT-immortalized Cells

All experiments should include physiologically relevant controls. ATCC provides primary keratinocytes and melanocytes, as well as hTERT-immortalized keratinocytes, microvascular cells, and fibroblasts which are used as controls for skin cancer cells. Primary and hTERT-immortalized cells may also be used to create 3D cell culture models to better represent an in vivo environment.

Primary Keratinocytes

Primary Melanocytes

hTERT-immortalized Fibroblasts

hTERT-immortalized Keratinocytes

hTERT-immortalized Microvascular cells

Skin Cell Lines

ATCC's vast collection of melanoma, keratinocyte, and fibroblastic cell lines derived from the epidermis and dermis includes cells derived from the normal and diseased tissues of multiple species.

Melanoma Cell Lines New!

Skin Cell lines