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Cell Line Genomic DNA

Highly purified genomic DNA preparations are critical controls in the development and validation of molecular assays.

ATCC has isolated and purified genomic DNA from a number of the highly characterized, authenticated cell lines in our collection. Specification and characteristics of each lot of genomic DNA includes: 

  • ddPCR™ quantitated for high-precision analysis*
  • Next-generation sequenced
  • Well-characterized genetic alterations
  • Absolute mutation/amplification copy number*
  • STR profiling to ensure identity
  • Mutations such as BRAF, KRAS, and EGFR
  • Amplifications such as HER2, EFGR, and MYC
  • PTEN deletions

  • *Quantitative DNA only

    The new Quantitative Genomic DNA are especially compatible with several lab-developed and commercially available assays as BSL-1, ready-to-use controls for your assays. 

    Quantitative Genomic DNA

    Quantitative Genomic DNA

    ATCC qDNA are extracted from patient samples or cell lines that contain biomarkers that have been quantified by validated methods for each product lot. Gene mutation allelic frequency as well as relative and absolute gene copy number are available for each qDNA. 

    Certified Reference Materials

    Human CRM DNA

    Genuine Nucleic CRMs are quantified biological reference materials produced under an ISO Guide 34:2009 accredited process to confirm identity, well-defined characteristics, and an established chain of custody. These tools are ideal for use in inclusivity/exclusivity testing, establishing limits of detection, and validating or comparing test methods.