MYC Genetic Alteration Cell Panel (ATCC® TCP-1035)

Organism: Homo sapiens, human  / 

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Organism Homo sapiens, human
Components ATCC CRL-1647 ST486
ATCC CRL-1648 CA46
ATCC CRL-5974 SNU-16
ATCC CCL-240 HL-60
ATCC CRL-9068 NCI-H929
Applications This validated panel is composed of 9 select human tumor cell lines carrying c-myc mutations or various degrees of c-myc gene copy number changes, and is useful for MYC pathway research and for anti-cancer drug discovery.
Biosafety Level 2  [Cells contain Herpesvirus (EBV)]

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments MYC is an oncogenic transcription factor which is encoded by the c-myc proto-oncogene. By regulating target gene expressions, MYC has diverse roles involved in cell growth, proliferation, biogenesis, cellular metabolism and apoptosis. Mutations or overexpression of c-myc gene has been detected in a wide range of human cancers, especially in lymphomas. The MYC genetic alteration cell panel (ATCC TCP-1035) is composed of nine selected human tumor cells that carry c-myc mutations or various degrees of c-myc gene copy number changes. The MYC status of each cell line has been sequenced and validated by ATCC. This panel is useful for studying MYC and its cellular effects on subsequent target genes and pathways in providing a platform for basic research and anti-cancer drug discovery.
Product Format 9 cryopreserved cell lines
Storage Conditions liquid nitrogen vapor phase (less than -130┬░C) only
Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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