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Michael J. Fox Foundation

The Michael J. Fox Foundation LRRK2 Cell Lines Collection

Michael J. Fox Foundation for Parkinson’s Research

ATCC has been selected by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to provide vital cell lines to academic, pharmaceutical, and biotechnology organizations committed to speed a cure for Parkinson’s disease. We have available macrophage cell lines, including wild-type LRRK2, LRRK2 knockout, and human LRRK2 T1348N (GTPase-dead) knockin, to advance the understanding of Parkinson’s disease and further drug development toward new therapies for the millions living with this disease.


The MJFF cell lines are distributed under the additional terms of the Addendum for MJFF Materials. It is required that the Addendum be signed and returned to ATCC prior to shipment.

In addition to the foregoing, this product's use is governed by the Zinc Finger Nuclease (ZFN) Label License Agreement. For information on purchasing a license to use this product for purposes other than those permitted in the Label License Agreement, please contact MilliporeSigma.

Available Cell Lines

Name ATCC No. Cell Count
LRRK2 Parental (WT) SC-6003 ≥5 x 106 total cells/ampule
LRRK2 KO SC-6004 ≥5 x 106 total cells/ampule
LRRK2 T1348N SC-6005 ≥5 x 106 total cells/ampule