It depends on the individual panel. The molecular signature panels, which focus on cancer genes or key components of cell signaling pathways, may include a wild type control cell line of specific gene (such as p53 hotspot mutation cell panels). If a wild type control cell line is not included in the panel, recommended wild type control cell lines can be ordered separately within the panel datasheet (such as EGFR genetic alteration tumor cell panel). Control cell lines are not included in tumor cell panel by tissue type. The researcher can choose normal tissue derived cell lines, primary normal tissue cells or hTERT immortalized normal tissue cells as control for tumor cells.
|Date Created||10/15/2013 11:36 AM
|Date Updated||03/27/2014 08:39 PM