Abstract: Angiogenesis is a multi-step physiological process that is involved in a large number of normal and disease state processes. In this webinar, we will introduce the Angio-Ready™ Angiogenesis Assay System, an in vitro co-culture system for measuring angiogenesis, which consists of an assay-ready mixture of an hTERT-immortalized human aortic endothelial cell line (TeloHAEC-GFP) and an hTERT-immortalized adipose-derived mesenchymal stem cell line (hTERT-MSC) in a specially formulated medium. Both cell lines have been highly characterized to verify that they retain the most important characteristics of their parental counterparts. The new co-culture system forms functional tubular structures in less than 7 days and responds appropriately in a dose-dependent manner to known agonists and inhibitors of angiogenesis. Thus, Angio-Ready™ is a ready-to-use, time-saving, high-throughput model for screening drugs or biomolecules for their effect on angiogenesis in cancer, toxicology, diabetes, cardiovascular disease, wound healing, and other pathologies.
- Angio-Ready™ is a ready-to-use, scalable assay system for angiogenesisis
- Live imaging is possible with this in vivo-like model consisting of fine tubular structures formed in less than 7 days
- The formation of vascular tubules responds appropriately to agonists and inhibitors of angiogenesis