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Introduction to ATCC® Microbiome Standards

An End-To-End Solution for the Standardization of Microbiome Research

9/7/2017

Abstract:

The complexities involved in 16S rRNA and shotgun metagenomic analysis methods pose significant challenges for microbiome research. Significant biases can be introduced during PCR amplification, library preparation, sequencing, and analysis. One of the primary obstacles in assay standardization is the limited availability of reference materials. To support this need, ATCC has developed microbiome reference standards from fully sequenced and characterized ATCC strains. To further enhance the use of these standards, ATCC has collaborated with One Codex to develop an easy-to-use data analysis module that enables researchers to analyze both shotgun and 16S rRNA data quickly and accurately while eliminating the biases associated with data analysis. In this webinar, we will discuss the need for standards in microbiome research, the development and use of the ATCC® Microbiome Standards, and how to analyze these standards using the One Codex data analysis platform.

Key Points:

  • One of the primary obstacles in the standardization of microbiome assays is the limited availability of reference materials
  • ATCC has developed microbiome reference standards from fully sequenced and characterized strains for use as daily run controls and in assay development
  • To eliminate bias associated with data analysis, ATCC has collaborated with One Codex to combine the power of physical laboratory standards with the leading bioinformatics platform for microbial genomics