ATCC offers well-characterized cells that can be used to refine traditional cell-based experiments or construct high-throughput assays, reducing the need for in vivo studies.
Physiologically-relevant cell-based assays are critical for the biomedical and toxicity data that cannot be obtained from animal models or humans. ATCC provides the cells needed to explore lung, skin, cardiovascular, gastro-enteric, liver, kidney, and neural toxicity for such applications as high-content screening, 3D culture, spheroid culture, permeability assays, metabolic stability and survival, and more.
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Renal Uptake Screening Tool
ATCC offers OAT1 HEK 293T/17 cells, which stably express organic anion transporter 1 (OAT-1), a renal uptake transporter that plays a key role in the kidney’s clearance of drugs and endogenous compounds. This cell line is a superior model for nephrotoxicity screening and renal physiology.
OAT1 HEK 293T/17 Cells
ATCC’s holdings include a vast collection of cell lines derived from kidney, representing the normal and diseased tissue of multiple species. Many of these cells can be used to build reliable models for the study of urolithiasis, renal function, glomerulonephritis, and kidney cancer.
Browse Kidney Cell Lines
Physiologically Relevant Controls
All experiments should include physiologically relevant controls. ATCC offers both primary and hTERT-immortalized renal epithelial cells. We offer cells from the renal proximal convoluted tubule, the renal cortex, mixed epithelial cells. Theses cells are well-suited for the study of normal renal physiology, toxicological screens, and can be used in drug discovery applications.
Primary Kidney Cells