Karyotype
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multiploid. The cell population has several ploidy indices.
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Derivation
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The HCC1599 breast cancer cell line was initiated on March 28, 1995, and took 10 months to establish.
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Clinical Data
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44 years
An EBV-transformed lymphoblastoid cell line (HCC1599 BL) from the same patient is available as ATCC CRL-2332.
Caucasian, White
female
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Receptor Expression
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estrogen receptor, negative progesterone receptor, negative
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Genes Expressed
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Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
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Cellular Products
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Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
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Comments
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The tumor was classified as a TNM stage IIIA, grade 3, invasive ductal carcinoma. Information regarding lymph node metastasis is not available. The cells are poorly differentiated. The cells are negative for expression of Her2-neu and for expression of p53. The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). HCC1599 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2), and for cytokeratin 19. An EBV-transformed lymphoblastoid cell line (HCC1599 BL) from the same patient is available as ATCC CRL-2332.
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